For my last game, I had revised the Depth Chart and placed some players on inactive/active. The game was played with out those changes and I am not sure if I missed something? Do I need to somehow save?

Are the players still marked inactive? It should not have played inactive players, and once you deactivate them in the depth chart you shouldn't need to do anything further.

Hey wolf! Changes save automatically. Let's wait for JD, but I bet somehow you got rexed

Feels like I got Rexed.

Hey Wolf, do me a favor and make some adjustments to your depth chart active/inactive, then go back to your team page and make sure that the appropriate players are inactive on your roster (they will display in a gray italic font). It shouldn't give you feedback on the depth chart screen (showing the player as inactive, updating the count at the top) unless the change successfully made it to the server and back.

Rex will kick in if you have fewer than 45 players active, though.

I only had 42 active so that must have been it. I'll adjust and see what happens if I keep 45 active. I have a ton of injuries so I was keeping folks inactive for that reason.

Hey wolf, thought I would not that here you say keep 45 active. JDB said fewer than 45. Someone correct me if i'm wrong but I believe you have to have 46 active, no more no less or you'll get rexed I guess

There is a 1 player grace :-)

okay, that is nice to know and thanks for correcting me on that one